MoDOT says the accident is at the 88 mile marker at Stafford.
At 5:00 am, the truck was in the median, with all westbound lanes closed. The left eastbound lane is also blocked. MoDOT says it may take up to three hours to clear up the scene.
Traffic is being detoured at the Strafford exit to the outer road to Highway 744, then back onto I-44.
Copyright 2016 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.