The win gave South Dakota its first ever Missouri Valley Football Conference Victory, and denied the Bears their first 2-0 conference start since 1997.
Bears QB Kierra Harris was knocked out of the game with a concussion in the fourth quarter. He will undergo further evaluation on Monday.
The Bears face the two-time defending national champion North Dakota St. Bison next Saturday.
Evangel improved to 2-2 on the year at Plaster Stadium, defeating Culver-Stockton 34-28.
SBU fell to 15th-ranked Washburn in Bolivar, 44-21.
Copyright 2015 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.