Her son told CBS News that she died Tuesday morning. The Humphrey Bogart estate also confirmed the death.
Born Betty Joan Perske in New York City, she was the daughter of Jewish immigrants and first cousin to Israeli statesman Shimon Peres. As a teenager she became a model and caught the eye of director Howard Hawks. He changed her first name to Lauren; she took her mother's maiden name of Bacal, adding an L -- and her career took off.
Her film debut, in 1944'S "To Have and Have Not," immediately made her one of Hollywood's leading ladies. She also met her future husband -- the movie's star, Humphrey Bogart. Bacall was 19 and Bogart was 45.
They starred together again in "The Big Sleep" and later "Key Largo."
While the couple continued making movies, they also started a family. They had two children, Stephen H. Bogart and Leslie Bogart.
But in 1957 Bogart died of cancer. Bacall said she never got over the loss.
She was briefly engaged to Frank Sinatra and later married Jason Robards, with whom she had one child, the actor Sam Robards.
And she kept her career alive. She won Tony Awards for her Broadway performances in "Applause" and "Woman of the Year." She was nominated for an Academy Award for 1996's "The Mirror has Two Faces," in which she played the still-glamorous mother of a dowdy professor played by Barbra Streisand.
Bacall once worried her obituary would be all about Bogart. But stealing Bogie's heart was just the opening act in a career that lasted decades and made her one of the last of the stars of Hollywood's golden age.
She uttered some of the most memorable lines in cinema history. In "The Big Sleep," Bogart's Philip Marlowe asks her, "What's wrong with you?" Bacall's Vivian Rutledge replies, "Nothing you can't fix."
But her most famous line came in the movie "To Have and Have Not":
"You know how to whistle, don't you, Steve? You just put your lips together ... and blow."
In 2005, Bacall said she never realized how iconic that line would become.
"I had no idea, no idea that it would have that effect," she said.
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